llm-sc-curator

by Ken Furudate · indexed from pypi

Dynamic feature distillation framework for robust zero-shot LLM annotation.

LLM-scCurator is a Large Language Model–based curator for single-cell and spatial transcriptomics. It performs noise-aware marker distillation—suppressing technical programs (e.g., ribosomal/mitochondrial), clonotype signals (TCR/Ig), and stress signatures while rescuing lineage markers—and applies leakage-safe lineage filters before prompting an LLM. It supports hierarchical annotation (coarse-to-fine clustering and labeling) for single-cell and spatial transcriptomics data.

Indexed · not connectedai-infra
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llm

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